发明名称 |
PHENYLPROPENONE COMPOUNDS AND MEDICINES CONTAINING THE SAME |
摘要 |
Compound represented by general formula (1) or (2) and medicines containing the same, wherein R1, R2, and R3 represent each an alkyl or the like; R4 represents an alkyl, an alkoxy or the like; and -N(R5)R6 represents substituted phenylamino, substituted phenylpiperazinyl or the like. The compounds have potent ACAT inhibitory activities and can lower blood cholesterol level and inhibit the accumulation of cholesterol, thus being useful as prophylactic and therapeutic agents for human arteriosclerosis.
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申请公布号 |
CA2283257(A1) |
申请公布日期 |
1998.09.11 |
申请号 |
CA19982283257 |
申请日期 |
1998.03.03 |
申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
SAWADA, HARUJI;WATANABE, TSUNEKAZU;YOKOKURA, TERUO;AIYAMA, RITSUO;WADA, YASUE;HATANO, HIROSHI;URAKAWA, TAKAKO;YOSHIDA, YASUTO;MORI, WAKAE;OHISHI, KENJI;OHWAKI, MAKOTO |
分类号 |
C12N9/99;A61K31/12;A61K31/165;A61K31/455;A61P3/06;A61P9/10;A61P43/00;C07C45/74;C07C49/248;C07C49/255;C07C235/34;C07C235/38;C07D211/98;C07D213/74;C07D239/42;C07D295/04;C07D295/185;(IPC1-7):C07C49/255;C07D295/02 |
主分类号 |
C12N9/99 |
代理机构 |
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