发明名称 |
Pyrimido[5,4-d]pyrimidines pharmaceuticals containing them their use and processes for the preparation thereof |
摘要 |
Pyrimido[5,4-d]pyrimidines of the general formula n signal transduction mediated by tyrosine kinases, their use for the treatment of disorders, in particular of oncoses, and their preparation. Exemplary compounds are: 4-[(3-Chloro-4-fluorophenyl)amino]-6-[1-methyl-4-piperidinylamino]pyrimido[5,4-d]pyrimidine, and 4-[(3-Chloro-4-fluorophenyl)amino]-6-[trans-4-dimethyl-aminocycohexylamino]pyrimido[5,4-d]pyrimidine. |
申请公布号 |
ZA9701887(B) |
申请公布日期 |
1998.09.07 |
申请号 |
ZA19970001887 |
申请日期 |
1997.03.05 |
申请人 |
DR. KARL THOMAE GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG. |
发明人 |
FRANK HIMMELSBACH;GEORG DAHMANN;THOMAS VON RUEDEN;THOMAS METZ |
分类号 |
A61K31/00;A61K31/505;A61K31/519;A61K31/529;A61K31/535;A61K31/5375;A61K31/5377;A61K31/54;A61K31/541;A61K31/55;A61K31/551;A61P17/00;A61P17/06;A61P35/00;A61P37/00;A61P43/00;C07D487/04;C07D519/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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