| 摘要 |
<p>Isolated DNA encoding the catalytic subunit of a eukaryotic telomerase holoenzyme, such as the catalytic subunit of a yeast or human telomerase holoenzyme; the RNA transcript, which is expressed in primary human tumors, cancer cell lines and telomerase-positive tissues; and the encoded catalytic subunit protein. Methods of assessing cells for malignancy or an increased likelihood of progression to malignancy and methods of diagnosing or aiding in the diagnosis of development of malignancy in an individual are also described.</p> |
