摘要 |
A process for preparing a compound of formula (I, I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, wherein: J represents O or S; T represents a substituted or unsubstituted aryl group and T<1> is O or S; which process comprises reducing a compound of formula (II, II) or a tautomeric form thereof or a salt thereof or a solvate thereof, wherein T and T<1> are as defined in relation to formula (I), with a complex hydride reducing agent or a source of a complex hydride reducing agent; and thereafter, as required, preparing a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof. |
申请人 |
SMITHKLINE BEECHAM PLC;GILES, ROBERT, GORDON;LEWIS, NORMAN, JOHN;MOORE, STEPHEN;POOL, COLIN, RIPLEY;QUICK, JOHN, KIRBY;URQUHART, MICHAEL |
发明人 |
GILES, ROBERT, GORDON;LEWIS, NORMAN, JOHN;MOORE, STEPHEN;POOL, COLIN, RIPLEY;QUICK, JOHN, KIRBY;URQUHART, MICHAEL |