PEG-BOUND ALKALOID LIGANDS AND USE THEREOF

摘要

Polyethylene glycol monomethyl ether-bound alkaloid ligands (PEG-bound alkaloid ligands) are constructed and employed in the ligand-accelerated catalytic (LAC) Sharpless asymmetric dihydroxylation reaction (AD) with a range of olefins. The PEG serves as a scaffold which allows simple product separation, polymer-bound ligand recovery, and recycling of the chiral liquid phase support without a loss of catalytic activity or ligand acceleration.