发明名称 |
USE OF HEAT SHOCK PROTEINS TO DELIVER MOIETIES INTO CELLS |
摘要 |
The present invention relates to a method of delivering a moiety of interest into a cell comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell. The invention also relates to a method of delivering a moiety of interest into a cell capable of taking up a complex comprising the moiety of interest covalently linked to a heat shock protein comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell. Also encompassed by the present invention is a method of delivering a moiety of interest into an antigen presenting cell comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell.
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申请公布号 |
WO9835705(A1) |
申请公布日期 |
1998.08.20 |
申请号 |
WO1998US03033 |
申请日期 |
1998.02.18 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH;YOUNG, RICHARD, A. |
发明人 |
YOUNG, RICHARD, A. |
分类号 |
A61K38/00;A61K47/48;C07K14/145;C07K14/35;C07K14/77;(IPC1-7):A61K47/48 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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