发明名称 |
Pegylation process |
摘要 |
The present invention relates to the attachment of a polyethylene glycol (PEG) moiety to a target substrate. Processes for such attachment will be hereinafter referred to as "PEGylation" of the substrate. In particular, the present invention relates to a process for direct covalent PEGylation of a substrate, comprising the reaction of a halogenated PEG with the substrate wherein the halogen of the halogenated PEG acts as a leaving group in the PEGylation reaction. |
申请公布号 |
AU5773798(A) |
申请公布日期 |
1998.08.18 |
申请号 |
AU19980057737 |
申请日期 |
1998.01.28 |
申请人 |
POLYMASC PHARMACEUTICALS PLC |
发明人 |
GILLIAN ELIZABETH FRANCIS;DEREK FISHER;FAROOQ MALIK |
分类号 |
A61K38/00;A61K38/22;A61K38/46;A61K47/48 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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