发明名称 Factor VIIa inhibitors from Kunitz domain proteins
摘要 A potent serine protease inhibitor capable of inhibiting Factor VIIa, Factor XIa, plasma kallikrein, and plasmin is provided. The inhibitor is provided in a pharmaceutical composition for treatment of diseases where inhibition of Factor VIIa, Factor XIa, plasma kallikrein, or plasmin is indicated.
申请公布号 US5795954(A) 申请公布日期 1998.08.18
申请号 US19940206310 申请日期 1994.03.04
申请人 GENENTECH, INC. 发明人 LAZARUS, ROBERT A.;DENNIS, MARK S.
分类号 C12N15/09;A61K38/00;A61K38/43;A61K38/48;A61P7/02;C07H21/04;C07K14/81;C12N1/21;C12N9/99;C12N15/15;C12P21/02;C12R1/19;(IPC1-7):C07K14/81;A61K38/16;A61K38/57 主分类号 C12N15/09
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