发明名称 NOUVEAUX COMPOSES ET COMPOSITIONS LES CONTENANT UTILISABLES POUR LE TRANSFERT D'AU MOINS UNE SUBSTANCE THERAPEUTIQUEMENT ACTIVE, NOTAMMENT UN POLYNUCLEOTIDE, DANS UNE CELLULE CIBLE ET UTILISATION EN THERAPIE GENIQUE
摘要 The invention concerns novel of compounds of formula (I) in which: R1 and R2, identical or different are C6-C23 alkyl or alkenyl radicals, linear or branched or -C(=O)-(C6-C23) alkyl or -C(=O)-(C6-C23) alkenyl, linear or branched. X is the oxygen atom or an amino -NR3 radical, R3 being a hydrogen atom or an inferior alkyl radical of 1 to 4 carbon atoms; n is a positive whole number from 1 to 6; m is a positive whole number from 1 to 6, and when n > 1, m can be identical or different. The invention also concerns novel compositions of said compounds and of active substances in particular therapeutically, comprising at least a negative charge for inserting said active substances in cells. It concerns in particular novel complexes, of which the active substance consists of one or several nucleic acids, useful for cell transfection.
申请公布号 FR2759382(A1) 申请公布日期 1998.08.14
申请号 FR19970015805 申请日期 1997.12.12
申请人 TRANSGENE SA 发明人 BISCHOFF RAINER;HEISSLER DENIS;NAZIH ABDESSLAME
分类号 A61K47/18;A61K31/00;A61K31/22;A61K31/221;A61K38/00;A61K48/00;A61P7/00;A61P11/00;A61P11/04;A61P21/00;A61P43/00;C07C229/16;C07C237/08;C07H15/00;C12N15/87;(IPC1-7):C12N15/85;C12N5/10;A61K47/48 主分类号 A61K47/18
代理机构 代理人
主权项
地址
您可能感兴趣的专利