| 摘要 |
A novel multi-well culture plate consisting of an upper plate (24) having a peripheral skirt (16), which conforms to the dimensions of the standard 96-well plate, a top surface (22), and upper chambers (18) which are circular cylinders that extend through the plate (24). Between each row of upper chamber (18) and immediately following the last row of upper chambers, are rows of access ports (20). Below the upper plate (24) is a lower plate (32) that includes a matrix of 96 tear-shaped reservoirs (30) which are open at the top surface (34) and have a bottom wall. Each reservoir (30) in the lower plate (32) aligns with an upper chamber (18) and access port (20) of the upper plate (24), such that when the upper plate (24) is positioned on the lower plate (32), each upper chamber (18) and access port (20) of the upper plate (24) communicates with a corresponding reservoir (30) of the lower plate (32). A membrane sheet (42) may also be included on which cells are placed on the upper surface thereof and cultured.
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