发明名称 PROPYLAMINE DERIVATIVES AND METHOD OF PREPARATION THEREOF
摘要 <p>Propylamine derivatives having general formula (I) and quaternary bases thereof. Compounds (I) may be prepared by coupling a compound having formula (III) with a compound having general formula (IV) to produce a compound having general formula (V) and reducing the compound (V) to the amine having general formula (I). The coupling agent may be dicyclohexyl carbodimide and the reducing agent may be lithium aluminium hydride. Such compounds exhibit antispasmodic activity, wherein the propylamine derivative in combination with a proper carrier is used as an effective agent. Use of the propylamine derivative as an effective pharmaceutical substance, i.e. as an antispasmodic agent.</p>
申请公布号 SK279235(B6) 申请公布日期 1998.08.05
申请号 SK19930000066 申请日期 1991.08.07
申请人 HORGAN WILLIAM J. 发明人 HORGAN WILLIAM J.
分类号 A61K31/135;A61P25/04;C07C213/00;C07C215/54;(IPC1-7):C07C215/54 主分类号 A61K31/135
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