| 摘要 |
PROBLEM TO BE SOLVED: To obtain protein SAPAP 1 capable of specifically binding to the constituent molecule PSD-95/SAP90 occurring in the neural postsynapse and its related proteins through a specific amino acid sequence and useful for elucidation of the neurogenesis and development, diagnosis of various nervous disorders, etc. SOLUTION: This protein is an animal protein having an amino acid sequence of the formula or having an amino acid sequence practically identical with that of the formula. To obtain SAPAP 1, a cDNA sequence encoding the amino acid sequence of the formula or that practically identical therewith is inserted into a suitable expression vector and expressed in E.coil, etc. |
