Imidazolidinone derivatives, their acid adducts and therapeutic drugs for senile dementia

摘要

PCT No. PCT/JP94/01506 Sec. 371 Date Mar. 15, 1996 Sec. 102(e) Date Mar. 15, 1996 PCT Filed Sep. 12, 1994 PCT Pub. No. WO95/07906 PCT Pub. Date Mar. 23, 1995Imidazolidinone derivatives represented by a following general formula (1) or pharmacologically permissible acid addition salts with cholinergic activity (muscarine M1 activity) provide compounds useful for the therapy of senile dementia. <IMAGE> (1) (wherein R denotes a lower alkyl group which may be substituted by halogen, or the like, R1 and R2 denote identically or differently hydrogen atoms or lower alkyl groups, R3 denotes a formula <IMAGE> (wherein R4 denotes a lower alkyl group which may be substituted by halogen, or the like, q denotes 0 to 3, and R5 denotes a hydrogen atom or the like), m and n denote 0 to 3, p denotes 1 to 3, and X denotes an oxygen atom or sulfur atom).