MORPHOGEN-INDUCED LIVER REGENERATION.

摘要

Disclosed are therapeutic treatment methods, compositions and devices for maintaining liver function in a mammal, including means for regenerating lost or damaged hepatic tissue, means for enhancing viability and integration of hepatic tissue and organ transplants, and means for correcting liver function deficiencies, including means for enhancing diminished liver function due to tissue injury or disease. The methods, compositions and devices on this invention all provide a therapeutically effective morphogen concentration to the hepatic cells to be treated. Also disclosed are methods and compositions useful in a gene therapy or drug delivery protocol for correcting a protein deficiency in a mammal.