Dimethyl substituted oxymethyl cyclohexane derivatives for their insect repellency properties

摘要

Described is a method for repelling insects by use of oxymethyl cyclohexane derivatives of the structure wherein Z is methylene; n is 0 or 1; each of the wavy lines represents a carbon-carbon single bond or no bond; the dashed line represents a carbon-carbon double bond or a carbon-carbon single bond; each of R2, R5, R6, R7 and R8 are the same or different and each represents hydrogen or methyl; and R1 represents hydrogen, acetyl or ethoxycarbonyl with the provisos: (i) that n is 1 and each of the wavy lines represents a carbon-carbon single bond when R1, R2, and R6, are each hydrogen, R5, R7 and R8 are each methyl and the dashed line is a carbon-carbon single bond; (ii) n is 0 and each of the wavy lines represents no bond when R5 and R7 are each hydrogen and R6 and R8 are each methyl; (iii) R2 is methyl only when R1 is ethoxycarbonyl; and (iv) the dashed line is a carbon-carbon single bond only when R1 is hydrogen.