N-alkyl and N-acyl derivatives of 3,7-Diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
摘要
3,7-Diazabicyclo[3.3]nonanes and selected derivatives thereof of the general formula: <IMAGE> wherein Q=S; Z=CH2; and Y equals an N-acyl or N-alkyl group are disclosed as multiclass antiarrhythmic agents.
申请公布号
US5786481(A)
申请公布日期
1998.07.28
申请号
US19950545341
申请日期
1995.10.19
申请人
THE BOARD OF REGENTS, OKLAHOMA STATE UNIVERSITY
发明人
BERLIN, KENNETH DARRELL;GARRISON, GREGORY LYNN;SANGIAH, SUBBIAH;CLARKE, CYRIL ROY;CHEN, CHUN-LIN;LAZZARA, RALPH;SCHERLAG, BENJAMIN JACOB;PATTERSON, EUGENE STUART;BURROWS, GEORGE EDWARD