发明名称 Bicyclic isothiourea derivatives useful in therapy
摘要 PCT No. PCT/SE96/00162 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Feb. 9, 1996 PCT Pub. No. WO96/24588 PCT Pub. Date Aug. 15, 1996There are provided novel compounds of formula I <IMAGE> I wherein D represents alkyl C1 to 6; T represents a C3-5 saturated or unsaturated alkylene chain substituted by -(CH2)m-NXY; -O-(CH2)2-NH- substituted by -(CH2)m-NXY; or -U-(CH2)a-N(X)-(CH2)b-; and a, b, m, X and Y are as defined in the specification together with processes for their preparation, compositions containing them and their use in therapy. Compounds of formula I are expected to be useful inter alia in the treatment of neurodegenerative disorders.
申请公布号 US5786364(A) 申请公布日期 1998.07.28
申请号 US19960615254 申请日期 1996.03.08
申请人 ASTRA AKTIEBOLAG 发明人 MACDONALD, JAMES
分类号 C07D217/02;A61K31/155;A61K31/47;A61K31/472;A61P25/00;A61P43/00;C07C335/32;C07D217/04;C07D271/04;(IPC1-7):C07D217/02;C07C335/02 主分类号 C07D217/02
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