发明名称 |
METHOD OF MYASTHENIA DIAGNOSIS |
摘要 |
FIELD: medicine, immunoneurology. SUBSTANCE: method involves determination of titer of antiacetylcholine antibodies in patient serum blood. The parent patient blood is analyzed by addition of sheep erythrocyte 1% suspension (0.1-0.2 ml) treated with acetylcholine to 0.1-0.2 ml serum blood at 2-fold dilution. Mixture is incubated at 37-37.5 C for 50-60 min and then at the room temperature for 22-24 h. Patient blood is analyzed by the same procedure in 30 min after subcutaneous administration of proserine solution. Myasthenia is diagnosed if the parent titer is decreased by 4-fold or more. EFFECT: simplified method, decreased cost, high precision and specificity. 4 tbl, 5 exr
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申请公布号 |
RU2116650(C1) |
申请公布日期 |
1998.07.27 |
申请号 |
RU19960122333 |
申请日期 |
1996.11.19 |
申请人 |
PERMSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA |
发明人 |
BYKOVA A.A.;OL'KHOVSKAJA E.F. |
分类号 |
G01N33/53;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/53 |
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地址 |
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