摘要 |
The present invention relates to four novel Fc receptor-like proteins which are members of the Fc Receptor family. In particular, isolated nucleic acid molecules are provided encoding the human FcR-I, FcR-II, FcR-III, and FcR-IV proteins. FcR-I, FcR-II, FcR-III, and FcR-IV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists FcR-I, FcR-II, FcR-III, and FcR-IV activities. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders. |
申请人 |
HUMAN GENOME SCIENCES, INC.;OLSEN, HENRIK, S.;NI, JIAN;MURPHY, MARIANNE;RUBEN, STEVEN, M.;GENTZ, REINER, L. |
发明人 |
OLSEN, HENRIK, S.;NI, JIAN;MURPHY, MARIANNE;RUBEN, STEVEN, M.;GENTZ, REINER, L. |