NOVEL Z-VALACYCLOVIR CRYSTALS

摘要

2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl N-[(benzyloxy)carbonyl]-L-valinate crystals showing diffraction X-ray peaks at least at diffraction angles (2 theta , CuK alpha -ray) of 15.3 DEG , 21.3 DEG , 23.8 DEG and 27.2 DEG when measured by powder X-ray diffractometry. These crystals are scarcely hygroscopic, have a high crystalline purity, contain little impurities and are useful as an intermediate of valacyclovir employed as an antiviral agent.