发明名称 Controlled release drug delivery system
摘要 The present invention pertains to a controlled release pharmaceutical tablet having at least three layers, two barrier layers and one drug layer. The two barrier layers erode more quickly than the drug layer. All layers are formed from swellable, erodible polymers. The drug layer can have a different composition from the two barrier layers. The three layers can also differ in thickness. The pharmaceutical agent is contained in the drug layer and is released as the tablet layer swells to allow diffusion through the tablet layers, and as the layers erode. The barrier layers are made from swellable erodible polymers which erode away to reveal more of the drug layer, as the tablet dissolves.
申请公布号 US5783212(A) 申请公布日期 1998.07.21
申请号 US19960595660 申请日期 1996.02.02
申请人 TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 发明人 FASSIHI, REZA;YANG, LIBO
分类号 A61K9/20;A61K9/32;A61K9/46;(IPC1-7):A61K9/32;A61K9/30 主分类号 A61K9/20
代理机构 代理人
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