METHOD OF MAGNETIC RESONANCE IMAGING

摘要

The invention relates to a method of magnetic resonance imaging (MRI) of a living sample comprising the steps of hyperpolarising a hyperpolarisable gas ex-vivo and transferring the nuclear polarisation from the hyperpolarised gas to the nuclei of an MR imaging agent, that is not hyperpolarisable, that is exposed to a uniform magnetic field and that is introduced in contact to the hyperpolarisable gas, separating the hyperpolarisable gas from the MR imaging agent, administering the MR imaging agent to the living sample, exciting NMR transitions in the nuclei of the imaging agent and detecting an NMR signal thereof.