摘要 |
<p>Gona-1:3:5(10)-trienes of formula (I). (i) R = H, alkyl (opt. substd.) or acyl, alkoxyalkyl R1 = (2-4C) alkyl Y = CO (opt. ketalised), hydroxymethylene or acyloxymethylene, Z = CO, hydroxymethylene, alkyl hydroxymethylene, or acyloxymethylene Y and Z together may be 17-acyloxy-16:17-epoxy-ethylenic group. The angular H atoms and R1 of ring C are trans-anti-trans. As oestrogenic and antilipaemic agents and inhibitors of pituitary gonadotrophins.</p> |