发明名称 Human embryonic lung fibroblast diploid cell strain suitable for the production of virus and process for the production of varicella zoster virus using same
摘要 PCT No. PCT/KR97/00028 Sec. 371 Date Oct. 14, 1997 Sec. 102(e) Date Oct. 14, 1997 PCT Filed Feb. 15, 1997 PCT Pub. No. WO97/30147 PCT Pub. Date Aug. 21, 1997A human embryonic lung fibroblast diploid cell strain LBHEL(KCTC 0127BP) is highly susceptible to varicella zoster virus(VZV). A cell-free varicella zoster virus (VZV) is produced by (a) culturing the human embryonic lung fibroblast diploid cell strain LBHEL(KCTC 0127BP) of claim 1 in a culture vessel to give cultured LBHEL cells; (b) infecting the cultured LBHEL cells with VZV to give VZV-infected cells; (c) culturing and harvesting the VZV-infected cells; (d) disrupting the harvested cells to obtain a cell homogenate; and (e) centrifuging the cell homogenate to obtain a supernatant containing the cell-free VZV.
申请公布号 ZA9701238(B) 申请公布日期 1998.07.14
申请号 ZA19970001238 申请日期 1997.02.13
申请人 LG CHEMICAL LTD. 发明人 JEONG-MIN KIM;JOO-HONG PARK;BOK-RYEON PARK
分类号 A61K39/12;A61K39/25;C12N5/071;C12N7/00;C12N7/02 主分类号 A61K39/12
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