A non-steroidal analgesic anti-inflammatory adhesive preparation rendered by coating one surface of support with an adhesive containing S-(+)-2-(2-fluoro-4-biphenylyl)propionic acid and a styrene-isoprene-styrene block copolymer or S-(+)-2-(2-fluoro-4-biphenylyl)propionic acid and a modified copolymer in which methylmethacrylate is allowed to graft-polymerize on said copolymer, or with an adhesive containing S-(+)-2-(2-fluoro-4-biphenylyl) propionic acid, sodium carboxymethyl cellulose and sodium polyacrylate.