摘要 |
The present invention provides crystals of Ob protein, a process for their preparation, and methods for their use. The crystals provide a stable, solid form of the Ob protein that is suitable for X-ray studies, for purification and recovery during manufacture of the Ob protein, and for use as a pharmaceutical for treating obesity and conditions associated with obesity.
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申请人 |
ELI LILLY AND COMPANY;BRIGGS, STEPHEN, L.;CLAWSON, DAVID, K.;SCHEVITZ, RICHARD, W.;WERY, JEAN-PIERRE;ZHANG, FAMING |
发明人 |
BRIGGS, STEPHEN, L.;CLAWSON, DAVID, K.;SCHEVITZ, RICHARD, W.;WERY, JEAN-PIERRE;ZHANG, FAMING |