发明名称 |
METHOD OF PRODUCING A SUSTAINED-RELEASE PREPARATION |
摘要 |
A method of producing sustained-release microcapsules which comprises dispersing a physiologically active polypeptide into a solution of a biodegradable polymer and zinc oxide in an organic solvent, followed by removing the organic solvent; which provides a sustained-release preparation showing a high entrapment ratio of the physiologically active polypeptide and its constant high blood concentration levels over a long period of time.
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申请公布号 |
CA2275422(A1) |
申请公布日期 |
1998.07.02 |
申请号 |
CA19972275422 |
申请日期 |
1997.12.18 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
YAMAGATA, YUTAKA;MISAKI, MASAFUMI;IWASA, SUSUMU |
分类号 |
A61K9/14;A61K9/16;A61K9/52;A61K38/27;(IPC1-7):A61K31/27 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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