发明名称 STABILIZED PHARMACEUTICAL PEPTIDE COMPOSITIONS
摘要 Disclosed is a stabilized aqueous composition for administration to a patient comprising a biologically active peptide, a buffer, a quaternary amine-type preservative or disinfectant, and an osmotic pressure-controlling agent, which composition can be stored and used at room temperature. The buffer stabilizes the pH of the composition between about 4 and 6. The preferred buffer contains citrate and/or phosphate, and the preferred preservative or disinfectant is benzalkonium chloride. The composition protects the peptide contained therein from adhering to container surfaces, particularly in containers made of polymeric materials.
申请公布号 CA2166296(C) 申请公布日期 1998.06.23
申请号 CA19942166296 申请日期 1994.06.22
申请人 FERRING B.V. 发明人 HARRIS, ALAN;TENNHAMMAR-EKMAN, BIRGITTA
分类号 A61K9/08;A61K9/00;A61K38/00;A61K38/08;A61K38/11;A61K47/18;(IPC1-7):A61K38/11;A61K38/09 主分类号 A61K9/08
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