Protein conferring an inducible resistance to glycopeptides, particularly in gram-positive bacteria

摘要

PCT No. PCT/FR93/01264 Sec. 371 Date Sep. 7, 1995 Sec. 102(e) Date Sep. 7, 1995 PCT Filed Dec. 17, 1993 PCT Pub. No. WO94/14961 PCT Pub. Date Jul. 7, 1994The invention relates to a protein VanB involved, in Gram-positive bacteria, in resistance to glycopeptides, particularly to vancomycine, said resistance being of the type inducible by the vancomycine and non-inducible by teicoplanine. The invention also relates to the utilisation of fragments of nucleotides of the gene van B for the detection of resistances to glycopeptides.