| 摘要 |
Wound implant materials are described comprising a plurality of bioabsorbable microspheres bound together by a bioabsorbable matrix, such as in a freeze-dried collagen matrix. The microspheres preferably comprise over 30% of the volume of the material, and preferably have diameters of 10 mu m to 1500 mu m. The microspheres and/or the matrix preferably comprise a polylactic/polyglycolic copolymer, collagen, cross-linked collagen, hyaluronic acid, cross-linked hyaluronic acid, an alginate or a cellulose derivative. The resulting implants are stronger and more slowly resorbed than conventional collagen sponge implants. Better control over the porosity of the implant is achieved.
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