Bone marrow stimulation by certain glutathione analogs

摘要

Compounds of the formula (1) and the esters, amides, amide/esters and salts thereof, wherein YCO is gamma -glu or beta -asp; G* is phenyl glycine or glycine; Z is CH2, O or S; and X is a hydrocarbon radical of 1-20 C; are useful in stimulating the differentiation of bone marrow, mitigating the bone-marrow-destructive effects of a chemotherapeutic agent, and in potentiating the toxicity of chemotherapeutic agents.