IgA Fc binding protein from Streptococcus pneumoniae

摘要

IgAFcBP polypeptides and DNA (RNA) encoding such IgAFcBP and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such IgAFcBP for the treatment of infection, and bacterial infections. Antagonists against such IgAFcBP and their use as a therapeutic to treat infection and bactenal infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of IgAFcBP nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding IgAFcBP and for detecting the polypeptide in a host.