发明名称 TAXANE DERIVATIVES, METHOD OF THEIR PREPARING, PHARMACEUTICAL COMPOSITION
摘要 FIELD: pharmacy. SUBSTANCE: invention relates to preparing new 3,11-cyclotaxanes of the general formula (I). Cyclotaxane of the formula (Ia) can be isolated from plants of genus Taxus (compound of the formula (I) where R' = R'' - H). New cyclotaxanes of the formula (I) show antitumor activity. EFFECT: new taxanes, improved method of preparing. 9 cl, 1 tbla
申请公布号 RU2112770(C1) 申请公布日期 1998.06.10
申请号 RU19930004649 申请日期 1993.03.04
申请人 INDENA S.P.A. 发明人 EHTSO BOMBARDELLI;BRUNO GABETTA
分类号 A61K31/215;A61K31/22;A61K31/27;A61K31/337;A61K36/13;A61P35/00;C07C67/00;C07C67/293;C07C69/00;C07C69/618;C07C233/54;C07D305/14;(IPC1-7):C07C67/293 主分类号 A61K31/215
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