| 摘要 |
PROBLEM TO BE SOLVED: To facilitate implantation, improve operability at operation time, and excellently maintain its shape in an organism by containing bioabsorptive calcium phosphate cement and a bone induction factor. SOLUTION: An implant for ossification contains bioabsorptive calcium phosphate cement and a bone guiding factor. As bioabsorptivity of the bioabsorptive calcium phosphate cement, it is desirable to be a material of being completely absorbed in an organism within at least one to two years. Therefore, bioabsorptivity excellent cement, to put it concretely, β-TCP-MCP cement, particularly, β-TCP-MCPM-CSH cement is desirable. The bone induction factor (BMP) is desirable to be human BMP manufactured by a gene recombination technology. That is, it is a recombinational human bone induction factor (γ hBMP) prepared from a phenotypic transformation body containing a recombinational DNA containing base sequence to encode a human bone guiding factor. |
