ANTI-HUMAN VEGF RECEPTOR F1t-1 MONOCLONAL ANTIBODY

摘要

A monoclonal antibody which immunologically reacts with human VEGF receptor F1t-1, cells having the human VEGF receptor F1t-1, expressed thereon, and the like; a monoclonal antibody having an inhibitory activity against the binding of human VEGF to human VEGF receptor F1t-1; and the diagnosis and treatment of diseases wherein the pathological condition advances by abnormal vascularization, such as propagation and metastasis of solid tumors, arthritis in chronic articular rheumatism, diabetic retinopathy, prematurity retinopathy and psoriasis, by using the monoclonal antibody.