发明名称 Platelet aggregation inhibitors having high specificity for GP IIbIIIa
摘要 A peptide containing the tripeptide recognition sequences RGD or KGD in a cycle and an exocyclic group bearing a positive charge is provided. The compound is provided in therapeutic form for administration to a mammal and exhibits high specificity and potency as a platelet aggregation inhibitor without undesireable side effects.
申请公布号 US5756452(A) 申请公布日期 1998.05.26
申请号 US19950567977 申请日期 1995.12.06
申请人 GENENTECH, INC. 发明人 BURNIER, JOHN P.;GADEK, THOMAS;MCDOWELL, ROBERT S.
分类号 A61K38/00;A61P7/02;C07K7/02;C07K7/06;C07K7/56;C07K14/75;C07K14/78;(IPC1-7):C07K5/12 主分类号 A61K38/00
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