发明名称 |
Platelet aggregation inhibitors having high specificity for GP IIbIIIa |
摘要 |
A peptide containing the tripeptide recognition sequences RGD or KGD in a cycle and an exocyclic group bearing a positive charge is provided. The compound is provided in therapeutic form for administration to a mammal and exhibits high specificity and potency as a platelet aggregation inhibitor without undesireable side effects.
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申请公布号 |
US5756452(A) |
申请公布日期 |
1998.05.26 |
申请号 |
US19950567977 |
申请日期 |
1995.12.06 |
申请人 |
GENENTECH, INC. |
发明人 |
BURNIER, JOHN P.;GADEK, THOMAS;MCDOWELL, ROBERT S. |
分类号 |
A61K38/00;A61P7/02;C07K7/02;C07K7/06;C07K7/56;C07K14/75;C07K14/78;(IPC1-7):C07K5/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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