| 发明名称 |
RECOMBINANT ALZHEIMER'S AMYLOID PROTEIN |
| 摘要 |
<p>DNA sequences encoding .beta.-amyloid-related proteins associated with Alzheimer's disease are disclosed. Also provided herein is a DNA sequence encodi ng a novel protease inhibitor. These sequences are used in producing or constructin g recombinant .beta.-amyloid-related proteins and recombinant or synthetic immunog enic peptides. Antibodies generated against the recombinant proteins or immunogenic peptides derived therefrom can be used for cerebral fluid or serum protein diagn osis of Alzheimer's disease.</p> |
| 申请公布号 |
CA2057053(C) |
申请公布日期 |
1998.05.26 |
| 申请号 |
CA19902057053 |
申请日期 |
1990.06.04 |
| 申请人 |
CALIFORNIA BIOTECHNOLOGY, INC. |
发明人 |
SCHILLING, JAMES W., JR.;CORDELL, BARBARA;PONTE, PHYLLIS A. |
| 分类号 |
A61K38/55;A61K38/00;A61K49/00;A61K51/08;A61P1/00;C07K1/22;C07K14/00;C07K14/47;C07K14/81;C07K16/00;C07K16/18;C07K16/38;C12N9/99;C12N15/09;C12N15/12;C12N15/71;C12N15/863;C12P21/02;C12P21/08;C12Q1/68;C12R1/19;C12R1/91;G01N33/50;G01N33/53;G01N33/68;(IPC1-7):C07K14/81 |
主分类号 |
A61K38/55 |
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