发明名称 SUBSTITUTED TETRAHYDRO-1,3,5-TRIAZIN-2[1H]-THIONES AS ANTI-ATHEROSCLEROTIC AGENTS
摘要 This invention provides compounds of formula (1) having the structure wherein R1, R2, R3, R4, and R5 are each independently, hydrogen, halogen, alkyl, cycloalkyl, alkenyl, alkynyl, phenylalkyl, alkoxy, aryloxy, fluoroalkoxy, trifluoromethyl, alkylthio, alkylsulfony, -SCF3, nitro, alkylamino, or dialkylamino; R6 is hydrogen, alkyl, cycloalkyl, or arylalkyl; and R7 is alkyl, cycloalkyl, or arylalkyl or a pharmaceutically acceptable salt thereof which are useful as antiatherosclerotic agents.
申请公布号 CA2271728(A1) 申请公布日期 1998.05.22
申请号 CA19972271728 申请日期 1997.11.10
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 STEFFAN, ROBERT JOHN;MEMOLI, KEVIN ANTHONY;STRIKE, DONALD PETER;FAILLI, AMEDEO ARTURO
分类号 A61K31/53;A61P3/00;A61P9/10;C07D251/08;(IPC1-7):C07D251/08 主分类号 A61K31/53
代理机构 代理人
主权项
地址