VASOACTIVE EFFECTS AND FREE RADICAL GENERATION BY beta -AMYLOID PEPTIDES

摘要

A method is disclosed for treating and preventing diseases, wherein at least one of the causes of the disease is beta-amyloid peptide induced change in free radical production resulting in vascular endothelial dysfunction and vasoactivity, by antagonizing vascular free radicals in excess of functional equilibrium, (see the figure which shows the action of beta-amyloid on endothelial cells). An animal model for the disease is also disclosed.