发明名称 Phenyl spiroethercycloalkyl tachykinin receptor antagonists
摘要 The present invention is directed to certain novel compounds represented by structural formula (I) or a pharmaceutically acceptable salt thereof, wherein R<3>, R<6>, R<7>, R<8>, R<11>, R<12>, R<13>, m, n and the dashed lines are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis.
申请公布号 AU5239898(A) 申请公布日期 1998.05.15
申请号 AU19980052398 申请日期 1997.10.22
申请人 MERCK & CO., INC. 发明人 CHARLES G CALDWELL;YUAN-CHING CHIANG;CONRAD DORN;PAUL FINKE;JEFFREY HALE;MALCOLM MACCOSS;SANDER MILLS;ALBERT ROBICHAUD
分类号 C07D307/94;C07D405/10;C07D405/12;C07D413/10;C07D413/12;C07D417/10;C07D417/12 主分类号 C07D307/94
代理机构 代理人
主权项
地址