发明名称 |
MICROSCALE LIQUID HANDLING SYSTEM |
摘要 |
A microscale fluid handling system that permits the efficient transfer of nanoliter to picoliter quantities of a fluid sample from the spatially concentrated environment of a microfabricated chip to "off-chip" analytical or collection devices for further off-chip sample manipulation and analysis is disclosed. The fluid handling system is fabricated in the form of one or more channels, in any suitable format, provided in a microchip body or substrate of silica, polymer or other suitable non-conductive material, or of stainless steel, noble metal, silicon or other suitable conductive or semi-conductive material. The microchip fluid handling system includes one or more exit ports integral with the end of one or more of the channels for consecutive or simultaneous off-chip analysis or collection of the sample. The exit port or ports may be configured, for example, as an electrospray interface for transfer of a fluid sample to a mass spectrometer. |
申请公布号 |
EP0840886(A1) |
申请公布日期 |
1998.05.13 |
申请号 |
EP19960926099 |
申请日期 |
1996.07.19 |
申请人 |
NORTHEASTERN UNIVERSITY |
发明人 |
KARGER, BARRY, L.;FORET, FRANTISEK;ZAVRACKY, PAUL, M.;MCGRUER, E., NICOL;XUE, QIFENG;DUNAYEVSKIY, YURIY, M. |
分类号 |
G01N27/62;B01J4/00;B01J19/00;B01L3/00;B01L3/02;G01N30/02;G01N30/28;G01N30/46;G01N30/60;G01N30/62;G01N30/72;G01N35/08;G01N35/10;G01N37/00;H01J49/04;(IPC1-7):G01N1/14;G01N30/04 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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