发明名称 |
Positive correlation filter systems and methods of use thereof |
摘要 |
A number of optically active elements are provided that enable the performance of accurate, dependable chemical analysis in a medium having varying matrix backgrounds and substantial component interferences. Optical transfer cells are provided that include positive correlation filter systems adapted to accept near-IR radiation and to pass a wavelength from that radiation having high correlation with a particular analyte. A near-IR spectrometer apparatus for the measurement of analyte concentration in a complex medium is also provided. The apparatus features an optical transfer cell constructed according to the invention. The apparatus can be used in the non-invasive determination of blood analyte concentrations in a variety of mediums. Methods of measuring the concentration of a blood analyte in a mammalian subject are also provided. The methods entail the use of reflective near-IR radiation to interrogate a medium to obtain spectrally modified radiation. The radiation thus obtained is passed through an optical transfer cell constructed according to the invention to obtain a wavelength having high correlation with an analyte of interest and substantially no correlation with interfering constituents present in the medium. |
申请公布号 |
US5750994(A) |
申请公布日期 |
1998.05.12 |
申请号 |
US19950547145 |
申请日期 |
1995.10.24 |
申请人 |
INSTRUMENTATION METRICS, INC. |
发明人 |
SCHLAGER, KENNETH J. |
分类号 |
A61B5/00;G01N21/35;(IPC1-7):G01N21/35;G01N33/49 |
主分类号 |
A61B5/00 |
代理机构 |
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代理人 |
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地址 |
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