| 摘要 |
<p>Radicicol derivatives having an antityrosine kinase activity and represented by general formula (I) or pharmacologically acceptable salts thereof, wherein R?1 and R2¿ are the same or different and each represents hydrogen, alkanoyl, alkenoyl, tert-butyldiphenylsilyl, or tert-butyldimethylsilyl; R3 represents Y- R5 {where Y represents optionally substituted alkylene, R5 represents CONR6R7 (where R6 represents hydrogen, hydroxy, optionally substituted lower alkyl, optionally substituted higher alkyl, etc. and R7 represents hydroxy, substituted lower alkyl, etc.), CO¿2R?12 (where R12 represents substituted lower alkyl, optionally substituted higher alkyl, etc.), etc.}; X represents halogeno or is bonded to R4 to represent a single bond; and R4 is bonded to X to represent a single bond or represents hydrogen alkanoyl, etc.</p> |
