.ALPHA.-AMINO SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS

摘要

A compound of formula (I) or pharmaceutical acceptable salts thereof, wherein R1 is isopropyl, 2-methylbut-2-yl, phenyl, benzyl, or 1H-indol-3ylmethyl; R2 is n-octyl, phenyl, or phenyl substituted with methoxy, fluoro, or bromo, are matrix metalloproteinase inhibitors.