发明名称 Method of producing 3-amino-2-hydroxy-1-propanol derivatives
摘要 PCT No. PCT/JP94/01540 Sec. 371 Date Jul. 18, 1995 Sec. 102(e) Date Jul. 18, 1995 PCT Filed Sep. 20, 1994 PCT Pub. No. WO95/08530 PCT Pub. Date Mar. 30, 1995The present invention has for its object to provide an efficient and economical method for producing an 3-amino-2-hydroxy-1-propanol derivative and an oxazolidinone derivative derived therefrom, both of which are of use as intermediates for the production of drugs including HIV protease inhibitors. The invention relates to a method for producing an 3-amino-2-hydroxy-1-propanol derivative of general formula (2) <IMAGE> (2) (wherein R1 represents alkyl, aralkyl or aryl; R2 and R3 independently represent hydrogen or an amino-protecting group, provided, however, that both R2 and R3 are not concurrently hydrogen) and an oxazolidinone derivative derived therefrom.
申请公布号 US5744630(A) 申请公布日期 1998.04.28
申请号 US19950436344 申请日期 1995.07.18
申请人 KANEKA CORPORATION 发明人 INOUE, KENJI;AWAJI, HIROSHI;TAKAHASHI, SATOMI
分类号 C07C271/16;C07D263/24;(IPC1-7):C07D263/20 主分类号 C07C271/16
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