| 发明名称 |
NON-ANTIGENIC TOXIN-CONJUGATE AND FUSION PROTEIN OF INTERNALIZING RECEPTOR SYSTEM |
| 摘要 |
A conjugate of a toxin and a cytokine, and a fusion protein comprising a bispecific antibody that has a first specificity for a cell marker specific to a malignant cell and a second specificity for a region of IL-15 alpha , each optionally further comprising a radionuclide, are useful therapeutic reagents for treating leukemias and lymphomas.
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| 申请公布号 |
WO9816254(A1) |
申请公布日期 |
1998.04.23 |
| 申请号 |
WO1997US17924 |
申请日期 |
1997.10.14 |
| 申请人 |
IMMUNOMEDICS, INC.;GOLDENBERG, DAVID, M. |
发明人 |
GOLDENBERG, DAVID, M. |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61K47/48;A61K51/00;A61K51/08;A61P35/00;A61P35/02;C07K14/54;C07K14/715;C07K16/28;C07K16/46;C07K19/00;(IPC1-7):A61K47/48 |
主分类号 |
C12N15/09 |
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