发明名称 |
HUMAN MONOCLONAL ANTIBODY TO LYMPHADENOPATHY ASSOCIATED VIRUS |
摘要 |
Human monoclonal antibodies capable of specifically reacting with an antigenic determinant of LAV/HTLV-III and cell lines producing those monoclonal antibodies are disclosed. The human monoclonal antibodies may be utilized in a method for determining the presence of LAV/HTLV-III in biological samples, or in a method for separating specific antigenic determinants of LAV/HTLV-III from a mixture. Pharmaceutical compositions containing such a human monoclonal antibody, and a method for significantly reducing the infectivity of LAV/HTLV-III in animals using the composition are also disclosed.
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申请公布号 |
CA1339830(C) |
申请公布日期 |
1998.04.21 |
申请号 |
CA19870540255 |
申请日期 |
1987.06.22 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
MCCLURE, JANELA |
分类号 |
C12N15/02;A61K38/00;A61K39/395;C07K7/08;C07K14/00;C07K14/005;C07K14/15;C07K14/195;C07K14/705;C07K16/00;C07K16/10;C07K19/00;C12N5/00;C12N5/10;C12N15/00;C12P21/00;C12P21/08;C12R1/91;(IPC1-7):C12N5/28;C07K1/22;C12N5/24;A61K39/42;G01N33/569 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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