| 发明名称 |
Heterocyclic thioesters and ketones |
| 摘要 |
This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters having an affinity for FKBP-type immunophilines, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme acitivity. |
| 申请公布号 |
AU4259097(A) |
申请公布日期 |
1998.04.17 |
| 申请号 |
AU19970042590 |
申请日期 |
1997.09.09 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
GREGORY S. HAMILTON;JIA-HE LI |
| 分类号 |
A61K31/40;A61K31/404;A61K31/4439;A61K31/445;A61P25/16;A61P25/28;C07D207/06;C07D207/08;C07D207/16;C07D211/22;C07D211/30;C07D211/32;C07D211/60;C07D401/06;C07D401/12;C07D403/12 |
主分类号 |
A61K31/40 |
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