发明名称 HUMAN SULFONYLUREA RECEPTOR SURH
摘要 The present invention provides a human sulfonylurea receptor (SURH) and the polynucleotides which identify and encode SURH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding SURH and methods for producing the protein. The invention also provides pharmaceutical compositions containing SURH, agonists to SURH, or antagonists to SURH, and in the use of such compositions for the prevention or treatment of diseases associated with the expression of SURH. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding SURH for the treatment of diseases associated with the expression of SURH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding SURH, or anti-SURH antibodies which specifically bind to SURH.
申请公布号 CA2265466(A1) 申请公布日期 1998.04.09
申请号 CA19972265466 申请日期 1997.10.02
申请人 INCYTE PHARMACEUTICALS, INC. 发明人 AU-YOUNG, JANICE;BANDMAN, OLGA;COLEMAN, ROGER
分类号 G01N33/53;A61K38/00;A61P3/08;A61P3/10;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12Q1/68;(IPC1-7):C12N15/12;A61K38/17 主分类号 G01N33/53
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