CARBOHYDRATE-MEDIATED COUPLING OF PEPTIDES TO IMMUNOGLOBULINS

摘要

The present invention relates to methods for enzymatically coupling peptides to immunoglobulin molecules via carbohydrate residues of immunoglobulin molecules, and to immunoglobulin-carbohydrate-linked peptide ("ICLP") conjugates produced by such methods. ICLP conjugates have been found to be superior in eliciting an immune response when compared to unconjugated peptide.